[DyumanBhatt]

What is the alternative for him? Another major, or just not going to a university?

You can use payscale websites to judge what kind of pay a programmer that has gone to a college gets in relation to one that has not and compare to the costs of going to college.

In regards to hectic schedules and hardcore math... it's not THAT bad, and the harder it is the stronger he'll be coming out.

At the end of the day its about how will he differentiate himself to other programmers. When he's looking for a job without a college degree but with a few projects under his belt compared to a fresh college grad with a 4.0, it might be a coin toss on who they pick. What if the college grad also did some work on the side, or internships? It may tip the scales out of your brother's favor.