Blocking a market of 447 million people simply because you need to ask them to click "agree" before you use their personal data (which most people do anyway) sounds like a bad business decision.
Do you have examples? Wikipedia[1] only mentions these:
Instapaper (restored service in the EU in August 2018)
Unroll.Me
Klout (went defunct in 2018)
The Chicago Tribune (local newspaper)
The Los Angeles Times (local newspaper)