[tomp]

There is 0% chance that human genetics changed this much in the last 100 years (3-4 generations). Look at photos from 100 years ago, people were mostly thin.

So no, we’re not genetically predetermined to be hungry.

There’s something in our environment that’s messing with our circuits. Either some toxins (e.g. endocrine disrupters) or hyper palatable food (artificially engineered for max enjoyment and min satiety), or maybe something else.

[BuyMyBitcoins]

But this doesn’t dismiss the idea that some people are genetically predisposed to be far hungrier. While true cheap and abundant calories facilitate obesity, that probably synergizes with people who have naturally voracious appetites. Someone in the pre-industrialized past wouldn’t have been able to binge on so much calorie dense food, but they may very well have felt gnawing hunger more strongly than their peers.