[heavyset_go]

If that doesn't work out, I think they make a combination drug of naltrexone/bupropion if the naltrexone worked for you originally. The latter drug activates parts of the brain that are responsible for emesis and it works well with the reward blocking effects of naltrexone.

Good luck either way.

[froggit]

Bupropion also helps increase dopamine and norepinephrine levels within the synaptic cleft. It was somewhat helpful for me when I wanted to reduce smoking. I was able to go from losing my mind if I went 90 minutes without a smoke to losing my mind after 3-4 hours without a smoke. I've heard anecdotal evidence from people I know that it helped with weight loss.

Personally, I can say that while Bupropion didn't help me lose weight that it did at least help me stop gaining weight. I've never taken it with naltrexone though. In fact, I'm long-term opiod agonist therapy for chronic pain developed in my early 20s. This actually has more or less the opposite effect of opiod antagonists such as naltrexone. They've definitely had a negative effect on my ability to lose or maintain my weight, although I seem to have achieved some kind of balance where my body plateaus after a certain weight.