[RedditKon]

Same - Mounjaro / Tirzeparide is nothing short of life changing.

A question I often get is "how effective is it?"

The SURMOUNT-1 study released in April 2022 showed 22.5% average reduction in weight for people on the highest dose of Mounjaro. For a 250 lbs person who should weigh 150 lbs (so 100 lbs of extra weight), this would result in them losing 56 lbs or 56% of their excess weight.

For context, bariatric surgery has the following success:

- Gastric Band: 35% - 45% of excess weight lost - Gastric Sleeve: 60% - 75% of excess weight lost

The fact that a once a week injection is having results similar to bariatric surgery is insane, and this is only the early innings of this shift. Lilly has another drug in the works (will likely be released in late 2025) that is reporting better results than Mounjaro.

Wild and exciting times!

[machiaweliczny]

I wonder if somone studied „dragon breath” and „vacuuming” exercise vs surgery. I am 15 pounds overweight but I have a feeling that since doing these I look much better and don’t eat that much

[archon810]

The FDA recommended against it. https://www.fox29.com/news/fda-warns-against-eating-dragons-...

[machiaweliczny]

By „Dragon breath” I meant breathing exercise that works belly muscles, you exhale trough teeth

[archon810]

What drug are you talking about? I did some research and I can't find it. Only talk of them ramping up Mounjaro by 2025.

[joedevon]

Oh really? Got any more info on that drug?