[drcross]

Please correct me if i'm wrong but wasn't the initial research on this conducted on animal models where they were essentially starved to the point where they went into hibernation mode?

The point that I'd like to make is- if you think a comparison between hunter/gathers and the modern human is illustrative for a diet where our phenotype thrives best, sure, their food arrive at more irregular intervals than the modern human and they probably binged on what was in season at the time (which might give us pointers for our own diet) but I think the concept of perpetual calorie restriction as a full time human diet is infantile and quacky.

[mcculley]

This is exactly why I said, “I have not seen compelling evidence of this, but I know a lot of people believe it.”