I wouldn't really honestly recommend it like that, there are too many asterisks to say 'PSA ket should probably not be taken orally '
Oral has the least bioavailability, but unless one is taking dangerous doses what I've heard is it doesn't likely matter. People will lose so much more in the dosing runaway spiral than from administration method -- you're going to reach a stable point either way if you're holding a certain dose, I believe. I've heard oral is less than ideal for trying to maximize dose response time and efficiency for amount-taken, but IM for example even far outstrips oral or nasal (once again, as implied earlier, I only recommend and advocate for appropriately medically prescribed and dosed Ketamine.
Edit: also a bit of a wtf after the fact but who the heck is taking Ketamine subcutaneously? On first blush, that sounds certainly nightmarish compared to any of the other injection methods.
> Also PSA ket should probably not be taken orally as it will damage your bladder (it always does but I think oral ingestion is worse for this)
I'd like some data to support this.
My understanding is you're going to pee it out (or pee out the waste products from it) one way or another. Oral dosage lasts longer, so theoretically the time it spends entering your bladder is longer, but I don't see why it would be that much of a difference.
The main issue with oral usage is that it's much weaker, you need to take much more for similar effects.
But insufflation damages your nose and sense of smell, so oral is my preferred method.
I've never heard of taking it subcutaneously. I'd plug it long before I'd try that
Also PSA ket should probably not be taken orally as it will damage your bladder (it always does but I think oral ingestion is worse for this)