[tbalsam]

Don't forget your dose conversion curves across species, girl. ;PPPP

Also! You may find this Twitter very interesting as well.... ;P https://mobile.twitter.com/justsaysinrats?lang=en

(And good point on the K-hole, in completely naive users my understanding is that this would likely induce a K-hole under IV conditions, but also we have to remember there are dose curve spike flattenings that happen depending upon dosing delivery methods due to transporter saturation, for example, etc as well....)