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by chasil 1274 days ago
You might be aware of the pathway that generates melatonin.

It begins with tryptophan, which can be converted either into niacin or serotonin. Taking a niacin supplement with tryptophan will boost the opposing pathway.

Serotonin is itself the source of all melatonin.

Adjusting diet is not as controversial as a hormone supplement.

Do not attempt this while taking an SSRI, which can be deadly.

2 comments

> Do not attempt this while taking an SSRI, which can be deadly

Attempt what, taking vitamin B3 and SSRI antidepressants?

I think the op is talking about anything that helps create serotonin whilst taking a serotonin reuptake inhibitor is a bad idea and I agree....

I have seen the results of MDMA + SSRI when I was at a party many many years ago... The seizure that person had was full body ... All their muscles were tense... It was lucky we got them to hospital asap as they almost died (30 minutes to live the doctors said) and even at that point needed to be put in a medically induced coma for days... (I took this person to the hospital and heard the rest from the person's family)

Take before bed, or any time of day?