[ergonaught]

It isn't news. It's science.

"Further investigations are needed to clarify the precise immunological mechanisms driving this response and to evaluate whether an IgG4-driven antibody response affects subsequent viral infections and booster vaccinations. This is not only relevant for potential future vaccine campaigns against SARS-CoV-2, but also for new mRNA-based vaccine developments against other pathogens."

[phtrivier]

Well, it's science because it's the result from a study published in a respected peer reviewed journal.

However, it's also "news", because the hypothesis that getting boosted could make you _more_ sick is pretty, well, say, novel.

(Hypothesis still to be confirmed, I get it, but if I understand the other comments correctly,that's the jist of it ?)

Also, in médecine, pretty much anything that goes into the direction of "more sick people" is, well, "bad" news ? Again, maybe there is a silver lining here, and I don't know enough about the topic.

Or maybe it's just a "Burn After Reading" thing.

"I guess we learned not to do it again" ? (except, no, we'll have to do it again, and FSM knows what would have happened if...)

[1] https://youtu.be/SlA9hmrC8DU

[busymom0]

The flu shots have shown a similar problem during the 2009 pandemic which was first thought to be happening only in Canada but was later on confirmed in other countries too and also confirmed in ferrets

> "seasonal flu vaccination almost doubled the risk of infection with pandemic flu":

https://www.cbc.ca/news/health/flu-vaccine-paradox-adds-to-p...

> "Canadian researchers noticed in the early weeks of the pandemic that people who got a flu shot for the 2008-2009 winter seemed to be more likely to get infected with the pandemic virus than people who hadn't received a flu shot."

> The ferrets in the vaccine group became significantly sicker than the other animals, though all recovered. "The findings that we show are consistent with the increased risk that we saw in the human studies," Ms. Skowronski said.

https://www.theglobeandmail.com/life/health-and-fitness/heal...

[bitL]

"Since Fc-mediated effector function could be critical for viral clearance, an increase in IgG4 subclasses might result in longer viral persistence in case of infection."