Some nice historical context for many of the recent developments (e.g. why py3.11 is 30% faster), and other general topics (e.g. why certain languages denote variables using dollar signs).
You can look at the topic-shortcuts on the video timeline to see if any of these topics are of interest to you.
I'd normally just listen to the podcast version, while doing something else. I finished through Lex's interview with John Carmack in several installments.