[mattashii]

I don't think airplane hulls are designed for more than 1 Atm of pressure differential between cabin and the outside; according to the wikipedia article [0] on cabin pressurization normal values are between 540 and 690 hPa pressure differential are normal.

If the cabin has an overpressure event, the hull might pop like a balloon, leading to a decompression event.

[0] https://en.wikipedia.org/wiki/Cabin_pressurization

[userbinator]

Exactly. The humans aren't the problem, it's the plane itself.