[DiogenesKynikos]

Objectively, the vaccine is extremely low risk, and the benefit is orders of magnitude larger than the risk for almost all groups.

I understand that some people have an irrational fear of the vaccine, and I can even try to empathize with them to that extent. However, it still is very difficult to understand the level of opposition to something which is so simple (just two painless injections, each taking seconds to administer) and so overwhelmingly positive (a 90+% reduction in the chance of serious disease, in exchange for a vanishingly small risk).

Public health messaging in the US was terrible, but US public health agencies were extremely cautious with the vaccines. If they hadn't cared about testing the vaccines, the vaccines could have been rolled out by mid-2020. After all, the vaccines were formulated all the way back in January 2020, pretty much as soon as the viral RNA sequence was published. I think it's sad that people have the impression that the vaccines were not thoroughly tested, because they were actually subjected to an extremely high level of scrutiny. They weren't approved until full-scale phase-3 trials with tens of thousands of participants had shown that the risk of severe side-effects was minuscule (i.e., as low as in other approved, safe vaccines).

The vaccine saved on the order of a million lives in the US. It's one of the most unambiguously positive things developed by humankind. That's why the strident opposition is so difficult to understand - it points to something very wrong in society.