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by manmal 1312 days ago
Have you checked out butyrate? There are some sodium butyrate supplements on the market. And a Japanese probiotic with Clostridium butyricum which produces butyrate. Certain cells in the gut derive 70% of their energy (ATP) from butyrate. Butyrate deficiency => weak gut cells => inflammation + permeable gut lining.

„Protective Mechanisms of Butyrate on Inflammatory Bowel Disease“: https://pubmed.ncbi.nlm.nih.gov/30277149/

1 comments

I actually haven't heard about this, will definitely give it a shot, thanks! Where do you usually find information about this?
IMO /r/microbiome is a great resource. Reddit in general, eg the nootropics subreddit is a treasure trove also. You could also search for „ameliorates [insert problem] pubmed“ or „[problem] [potential solution] pubmed“ in the search engine of your choice, and if an abstract piques your interest, view the full paper on sci-hub.

One thing I‘d like to stress is that the internet is full of scams and counterfeit products, and you can only be (pretty) sure a supplement is legit if you order it directly from the manufacturer. I think iHerb also has really good quality control, FWIW. Patented extracts are IME also preferable over run of the mill extracts, some of them are orders of magnitude more effective.