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by scantis 1327 days ago
What does well understood mean in this context? The mRNA enters the cell because of some addition to it, which seems to be the key here. What is exactly coded in front of that spike protein to enter a cell and what happens with it inside the cell? Is this part required to enter the cell just discarded?

The cell starts production of viral protein by copying the mRNA again and keeps doing so for while. Then it somehow stops... What exactly stops this process, except for heat shock?

Are the cells injected with the mRNA gobbled up by the immun system or does it stop on its own to produce the viral protein?

How does the viral protein leave the cell after it is produced inside of it? For a production of a virus it would stay inside until the virus is fully assembled. Is there a trick to the mRNA stuff, that makes the cell produce the viral particles outside of itself so the immun system can get to it?

Or is the cell bursting at some point when it is completely overloaded with viral protein?

2 comments

I explained what happens at a level of abstraction that makes sense for what was being asked. If you want more details then get in touch with a real biologist or geneticist. I'm not the person to answer your questions.
The mRNA is misinformation that tells the cell to produce the spike protein of coronavirus on its cell membrane. Those membranes are how cells interact with their environment. Later immune cells interact with those same spike proteins to identify the right antibodies to fight off the foreign, spike proteins. All without ever actually exposing the patient to coronavirus.

Good luck.