The main drawback you have to keep in mind is that you cannot modify pool size. Every pool can have one or more volumes. For advanced features like ARC caching, I'm just using sensible defaults.
Also, keep in mind that ZFS need at least 8GB of RAM, possibly 16GB for up to 16TB of data.
Also, keep in mind that ZFS need at least 8GB of RAM, possibly 16GB for up to 16TB of data.