[spangry]

Number 3 is very interesting - Methionine is a crucial precursor to producing glutathione, the body's "master antioxidant". If the inflammation / oxidation hypothesis of depression that I'm spruiking is correct, then B-9 supplementation may help alleviate depression by increase synthesis of glutathione which is turn would reduce the level of free-radical caused neuro-inflammation.

I'm all for your particle-level simulation of the human body, I've had thoughts along similar lines (but unfortunately lack the skills and knowledge to implementation something like this).