The fact that the tiniest features of the cloud appear preserved between the two images gives an appreciation for how big it is. The two photos are taken 27 years apart
I'm more surprised by how much change there is. All the bluish stars in the JWT version are also in the Hubble version, but none of the yellowish. Is that parallax movement or are they obscured by the medium mentioned in the article? ("no galaxies")
The bluest ones in the JWST images are the higest frequency (shortest wavelength) it can see. These are the longest frequencies hubble can see, so they look reddish.
Anything in JWST that is lower frequency (yellow to red) will not be visible to Hubble