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by gus_massa 5312 days ago
I studied a Chemical specialization in the secondary school, but this is too difficult for me. I will keep trying, without seeing the video (I already have my two [Pyruvate]s!).

Some comments:

* Add an "undo" button. I'm not sure if it is possible to choose a bad reaction, but I’d like to undo some of the tries. (And perhaps a "restart+areyousure" button.)

* Add a lithe graphic to each molecule, so they look more real.

* Some reactions are too fast, for example [Glucose 6-phosphate] -> [Fructose 6-phosphate] is almost instantaneous, so it took me like a minute to realize that something had happened. You should add some delay and more highlighting.

* The page is very tall, so it is not possible to see at the same time the reactives and the enzymes at the bottom, like [Pyruvate kinase] or [ATP synthase].

* Add an "easy" mode, so that when you pick a molecule, all the possible enzyme targets are highlighted.

* If you put a [ATP] in the [Pyruvate transport] and you don’t got any [Pyruvate] then the [ATP] is splited, but no [Pyruvate] is transported. So you lost a [ATP] :( !! I don’t know if it is biology correct, but I would like that the [Pyruvate transport] is dissable / does nothing when there is no [Pyruvate]. (Same problem with the [NAHD transport].)

* If you put a [ADP] in the [ATP/ADP Translocase] in the Mitochondrial matrix side the [ADP] get stuck until you put a [ATP] in its place. First, it is not possible to remove the [ADP] from the enzyme. Second, I’m not sure, but it looks like that the enzyme is translocating the third phosphate from the [ATP] to the [ADP] on the same side of the membrane.

Nice work.

1 comments

Thanks for your suggestions! I've implemented a couple of them:

* Added delay for every reaction

* Made the page less tall, everything is smaller now (I'd underestimated the size, working on a 27" iMac)

* The easy mode was already there, enzymes lit up when you picked up a substrate. I've added an extra help now: when you hover over an enzyme, the available substrates light up.

* The transporters are only visible (and usable) if enough ATP/substrate is available

Now it doen’t work in IE8 (javascript error). But it works in Chrome. It looks much better in Chome than in IE8. I think that I didn’t see the enzymes highlighting because of IE8.

Please don’t make the transporters invisible, only disable them.

(I don’t like starting with a Pyruvate, it is like cheating.)