[gjvnq]

> There has never been any good scientific evidence that depression (or any other mental health issue for that matter) involves a “chemical imbalance”.

Transfem here. Gender Dysphoria is a hell of a condition and it usually improves massively as soon as people start taking cross-sex hormonal replacement therapy (HRT).

In my personal experience, it was almost like magic how quickly and how much I improved when my testosterone finally fell to zero.

[skissane]

You’ve wanted something for years and now at last you are getting it - that fact alone has to make a person feel happier and feel like the trajectory of their life is turning in a more positive direction. It is near impossible to determine what consequences of cross-sex HRT are due to its direct biochemical effects, and which are due to those kinds of psychological factors.