[sallystarace]

Dextromethorphan tolerance builds so rapidly. I have found the withdrawal to be hell after taking it legitimately for a cold longer than I realized. I have tried SSRIs and found that they also have a synergetic effect with Bupropion (good medicine). SSRIs also make me drowsy, but at least they can be sustainably taken daily for months.

[mmastrac]

I had good luck with a prescribed combo of modafinil + buproprion. No drowsiness, much higher motivation.

[hungrigekatze]

Does that lower the seizure threshold at all? (I've had docs get on my case about bupropion + mild other medication that can in theory impact the seizure threshold) But I'd be interested - potentially - in trying this combo as things are pretty cobwebby in the brain department lately.

[epicureanideal]

Modafinil alone didn’t have that effect?

[mmastrac]

It helped, but the combo beat both depression and lack of motivation much more effectively.

[gremlinsinc]

Sounds like me, except Vyvanse instead of Modafinol. Bupropion was the magic key. I thought my Vyvanse just wasn't working anymore.

Turns out I was just super depressed. Since switching meds I've lost a lot of weight because I don't have food cravings as much.

The way I think of it... Vyvanse keeps me focused when I get to work, but without Bupropion just getting out bed sometimes seems daunting. One gets me to start my day, the other keeps me focused when I do.

[floatinglotus]

What dosage of modafinil?

[mmastrac]

Pretty low, but I tend to find lower doses than average to be effective.