[arlort]

No

There is no codified legal process for a US state to leave the Union, and the only previous attempt caused a civil war

A member of the EU has both an implicit right to withdraw from the treaties (deriving from international customary law around treaties) and an explicit legal path to follow. A process which they control in their entirety (as in they can't be forced to stay longer than they wish by the other countries and can't be forced to leave earlier than the prescribed deadline)