[lyddonb]

I think this is more like it. We use the Django framework at work and I wish we could get rid of it. These big "do all" frameworks seem like a good idea but by the time you've hacked in all of your needs along with GAE's your begin to wonder why you ever started with.

[rbanffy]

The main reason is portability. The zero-admin scaling Google provides is very tempting and being able to port your Django app to App Engine can be a good advantage.

[StavrosK]

As well as being able to easily move off GAE if you need to. I think that's the biggest gain.