Really interesting chart on your lifestyle interventions link. Curcumin has both a very strong performance and pretty good range. Interesting to see that it is much more so than exercise or sleep improvements.
Relevant: “curcumin is a PAIN (pan-assay interference compound, ie a substance with weird chemical properties that make every test seem positive, so if you do chemical tests to see whether it activates eg coronavirus-fighting immune cells, it will always say yes). This means people are always publishing exciting papers about it and alternative medicine people are always getting really enthusiastic about it and suggesting it as the cure for everything (eg depression).”
From https://astralcodexten.substack.com/p/pascalian-medicine