[ssalazar]

> This means there might be something universal about octave and fifth

There is! At least for the kinds of instruments that are conventionally used in Western music. The harmonic series arises naturally from the physical properties of a string or wind instrument (e.g. violins, guitars, pianos, flutes, brass, organs, etc). As a very rough description of the physical phenomena, the tones we hear arise from a full spectrum, atonal excitation (like a pluck or a reed flapping) bouncing back and forth along the length of string or tube, which is basically a one-dimensional "waveguide". Frequencies that are aligned with the harmonic series naturally reinforce themselves, in the same way that putting energy at the top of the arc of a playground swing has more of an effect than in the middle.

Notably, musical instruments that are not strings or tubes, or more general sound-producing bodies, have more complicated patterns of sound waves dispersing through them, and don't typically follow the harmonic series. Pitched percussion, drum heads, or bells have more complicated harmonic spectra than the standard harmonic series (as they are generally thought of as 2D or 3D waveguides where cancellation/reinforcement patterns are less straightforward), as do less musically conventional sounds like knocking two rocks together or striking an arbitrary surface.