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by bilsbie 1388 days ago
I’m not getting it? Can you dumb it down?
2 comments

First off, I'm no doctor or even close.

In recent years there has been a back-and-forth discussion about whether being overweight is bad for your health. Intuitively one might think that being overweight is bad. But in 2015, for example, there was this article, which reflected a story making the rounds at the time:

https://qz.com/550527/obesity-paradox-scientists-now-think-t...

What I take this study to be saying is that obesity in itself is not really the problem, but it is (presumably) highly correlated with high A1C measurements and inflammation, which do indicate a poor state of the endocrine system (i.e., Type 2 diabetes), which can in turn lead to heart disease and stroke if not treated.

I'm hoping that someone who knows more than I do will poke some holes in what I have just written so as to give you a better answer.

>It’s true that these groups are slightly more likely to suffer from heart disease and some other life-threatening conditions in the first place. But many factors influence the likelihood of a person getting heart disease. And a strong link between weight and disease only emerges among people with severe obesity.

That seems like a place where the article should maybe have a citation or two.

One possible explanation is that obese people lack adequate muscle mass. The lack of muscle -- protein -- is associated with insulin resistance and it may be lack of muscle rather than additional fat per se that is one of the actual root causes of health issues associated with obesity and routinely attributed to fat per se.

https://news.ycombinator.com/item?id=14667430