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As far as size goes:

a) Compiled JS apps generally have to include a whole Javascript engine, which makes them significantly larger b) Rust is designed for shipping small static binaries, whereas Node is not; node.exe by itself is tens of megabytes, and you can only make it smaller by compiling it yourself from source. Deno has compiling static binaries as an explicit feature so it may fare better in the long run, but it's still limited by a)

As an example: I just tested on MacOS and a hello world program compiled with `rustc` is 378KB, whereas one built with `deno compile` is 74MB.