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I'd argue both those studies are insufficient to come to any conclusions because people do not exist for only one day, and they do not exist in only a healthy state. A healthy subject, say in their mid twenties, should be able to consume 60g glucose almost instantaneously and have little to no affect on blood glucose. That same subject, if they were to repeatedly do that, multiple times a day, for four decades, is highly likely to have Type 2 diabetes and a heart condition, also likely to have a kidney condition, peripheral neuropathy, macular degeneration, etc take your pick. The interesting question is what are the long term effects. There are no positive outcomes for a long term high sugar content diet, and I argue that taking any one plant derived, or synthetic chemical, concentrating it and consuming it, is either nutritively, or medically, beneficial, or, if not beneficial, will work, at least to some extent, to tax the body by making healthy homeostatic more difficult. As an aside, and this isn't directed at you in particular, but at the HN community, if such a thing can be said to exist, more broadly: frameworks. What frameworks exist within which do make sense of nutritional / health information. How are we to live? What are some (any?) of these frameworks, and where should we go to read about them? |
In terms of informational frameworks regarding nutrition I have to say the landscape is quite bleak. Understanding broccoli or its effects on the human body make big pharma no money, publications are only slowly picking up speed with new (crowd-) funding options. Even worse, the lack of funding and publishing set a rather low barrier for food industry players to manipulate the field in their favor, which makes for even less solid ground (e.g. https://www.nytimes.com/2016/09/13/well/eat/how-the-sugar-in... ).
But there are exceptions, Rhonda Patrick comes to mind, she's mostly or fully crowdfunded, including her papers iirc. She can go very deep but is usually aimed at non specialists: https://www.youtube.com/c/FoundMyFitness/videos
And Andrew Huberman who finances his podcast through sponsors, quite dense but always trying to explain medical terms and concepts he brings up: https://www.youtube.com/c/AndrewHubermanLab
As for "how are we to live" I think a good starting point nutritionally is to try and watch/feel the body reacting to different foods and maybe reading up after something feels really good or bad to maybe gain some theoretical insights. There are no studies for your body in particular but you have full production test access pretty much all of the time (I would try to prevent restarts though).