[41b696ef1113]

While it does not address the root question, one benefit of sugar substitutes is that they are many times sweeter than sugar: stevia is 200-300x sweeter, resulting in less total mass consumed. My hopelessly-naive-because-biology thought is that each molecule would be metabolized a single time (by your own liver or your microbiome), resulting in less total impact on your body.

[vanilla-almond]

I also find using less stevia than the equivalent sugar amount. I still have a sweet tooth but I don't buy sweet foods (make my own sweet foods with stevia).