[VLM]

Generally life extension runs up against three non-technical problems:

Addicts will fight VERY hard in support of their addiction. Try telling a life long sugar addict to fix their T2 diabetes by eating fewer carbs; they'll completely explode at you. People who die from smoking were usually told about a million times to quit smoking before their diagnosis, LOL.

Innumerate people seem to actively oppose statistics. There is only it works or it doesn't and they'll have a complete meltdown at the concept that maybe 80% of lung cancer is caused by smoking and 20% for other causes therefore there is nothing they can do to alter their pre-determined destiny. Arguably belief in predestination and/or innumeracy could be considered a mental illness (see below) but I'm specifically referencing the stubborn desire to beat the odds by ignoring the odds. (edited to emphasize, the type of thing I'm referring to is the aggressive proselytization of the idea that finding one counterexample or anecdote disproves the entire corpus of all theoretical and applied statistical mathematics)

Most people decline and die younger for some kind of psychological reason. They're depressed so they can't do anything so they can't exercise so they get fat and die of a heart attack, they did in a certain technical sense die because they were fat, but they got fat because they were depressed. Or they have an addiction problem. Or they follow quacks because they think if martyrdom is religiously superior then punishing themselves is superior even if it shortens their life, or they follow medical advice based mostly upon making money off prescriptions, or they follow medical advice that was proven obsolete via research last century, or they are so into collectivism and "fitting in" that they would literally rather die than think for themselves or read a book, whatever the TV (or social media) says is not just good enough, but should be forced on people, even if it kills them.