[marcosdumay]

The difference in entropy is so small that we are talking about entropy of dissolution. It's not hard on those conditions to introduce some element that weakly bias the reactions on a different way.

I don't want to minimize the gaps on our knowledge. We don't know how any macromolecule polymerization occurred. But I also don't want to maximize the gap. Those kinds of reaction are completely mundane and occur on a huge variety of environments. The fact that we don't know what environment it was doesn't mean it's an outwordly phenomenon. And adding just a few of those mundane reactions is enough for life to appear.

(Anyway, I question your certainty about the concentration of water on our primordial oceans. Abiogenesis research usually uses a model of water origins that gives a precise estimation for its amounts, but not only we know that this model is wrong - water is cycled by geologic means like any other mineral - but we also do not have anything with near that amount of precision to the other substances that composed it.)