Wow. I don't know anything about screen readers or how blind people use the web, but I'm surprised that a strictly text website like HN would be inaccessible to blind people.
Sina is great, it's a shame the device output is so much louder than his microphone in the video.
I didn't hear him mention the lack of skip links on HN's home page (skip links are more for sighted keyboard users than blind screen reader users like him), I did hear him mention that the stories on the home page are not headings. Yes, a screen reader can navigate link to link but there are ~7 non-story links between each story link so being able to navigate from story to story as headings would be really helpful and semantically accurate.