[zvr]

Having used many *roff variants (e.g., troff, nroff, ditroff, groff) over decades and also having rather extensive experience with LaTeX, I'd now definitely choose the latter for any serious typesetting task.

Pain points include many customization points: re-creating exact document specifications provided externally, using specific typefaces, creating your own macros... Oh, and leaving ASCII (or ISO-8859-1) for multi-script characters.

Today's groff is a very fine software, if you are satisfied with its default settings and your task is in the domain it handles.

[veltas]

groff can do all of the above. The big issue is finding the documentation for it.

[zvr]

Oh, I know how to do most of these, by now. But they are still pain points.