[WorldMaker]

It's also useful to note that stress in the brain also in some cases increases neural activity which increases oxygen needs by the brain as well as electrolyte needs by the brain. The increase in oxygen usage increases strain on the heart and can indirectly cause heart disease/heart attack. The increased consumption of electrolytes if not carefully managed can cause strokes. Especially in that latter case, burnout that results in a stroke is a very literal burnout, the brain has electrically burnt too hot/bright and the resulting damage is very real and very scary.