[joshink1]

My spouse also has PSC w/o IBD, 13 years now since diagnosis. We were given a poor prognosis 5 years ago but Vanco has stabilized her MELD score (indicator for transplant) and has been somewhat stable since. The Mayo Clinic in AZ has been very helpful after many hospitals rejected our desire to use experimental treatment.

NOTE: There are some generic equivalence issues having to do with the coating, make sure you research the manufacturer (ANI seems well tolerated, Alvogen not so much).

[8crazyideas]

I'm happy to hear about your spouse. I actually published a case report that included observations about the importance of brand. One of the capsules tested didn't dissolve until the ph reached 9, clearly not physiologic. ANI, Lupin and Firvanq (liquid) seem to work.