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by teyc
5335 days ago
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Incidentally my sister just got a paper published in the New England Journal with a similar approach (kill switch) for use in gene therapy http://www.nejm.org/doi/full/10.1056/NEJMoa1106152 This could be pretty important work to make gene therapy much safer. A single dose of dimerizing drug, given
to four patients in whom GVHD developed,
eliminated more than 90% of the modified
T cells within 30 minutes after
administration and ended the GVHD
without recurrence.
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