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by MuchoMaas
1447 days ago
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I find all these mandates silly, but in a way this makes more sense than the places here in the US which have a vaccination requirement but still accept proof of shots from early/mid 2021, which are known to have worn off long ago at this point. |
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Why not? Well, they tried. Moderna did a trial of an Omicron vaccine. It failed because the vaccinated population simply generated antibodies against the 2019 WIV strain "wild type" spike, not the Omicron spike. It only worked in the unvaccinated, but that's not a market for obvious reasons.
The underlying issue appears to be a form of imprinting or lack of resolution. Our bodies lack the ability to quickly differentiate the different spikes. The immune system just says, ah ha, a spike! I know what to do now, I've seen this problem before! Then it generates antibodies that don't bind properly, which is why the boosted are now getting so frequently sick with COVID even just months apart, which isn't meant to happen. In normal times, even after the virus mutated such that the body can't tell it apart from earlier variants, it doesn't matter because the virus keeps hitting people who were never previously infected and whose immune systems thus develop properly targeted antibodies. It acts as a firebreak and slows the whole thing down pretty dramatically, which is why most people can go many years without re-catching flu. But now we've broken that diversity by homogenizing the entire population. Almost everyone has now been imprinted with a spike that's long since extinct in the wild, so there's no firebreak anymore.
Given that context, insisting on COVID vaccine every nine months is catastrophic. It won't slow down Omicron, it would only make it worse, and the spike protein is cytotoxic. It's not at all free to repeatedly flood your system with it.