[shawabawa3]

Up until the point where you want to immediately remove it all (when you fall asleep)

[an9n]

Well indeed, but they say you should take this before you start drinking! An hour or two before you want to stop, perhaps.

[im3w1l]

In the test they ran they even had people take a pill every day for a week in advance. These are bacteria so it kinda makes sense that it a takes a while for them to get cozy.