Pretty sure you can figure out why, but if you deny this line of vaccines that are the oldest in existence from variolae vaccinae, Jenner's Latin for "smallpox of the cow," you deny everything called a vaccine.
Given that the only new wrinkle on Orthopox vaccines is taking the old derived from cowpox virus and preventing it from reproducing which is not a new or likely to be difficult technique including in manufacturing, there's effectively nothing "new fangled" about them.
Nor should there be anything "eye wateringly expensive" about them except Bavarian Nordic's JYNNEOS perhaps having a monopoly on this new type for now (they do in the US, don't know about Europe). For the older type vaccine the US started making it again after 9/11 so reclimbing the learning curve was done long ago, there's 100 million doses in our stockpile.
Given that the only new wrinkle on Orthopox vaccines is taking the old derived from cowpox virus and preventing it from reproducing which is not a new or likely to be difficult technique including in manufacturing, there's effectively nothing "new fangled" about them.
Nor should there be anything "eye wateringly expensive" about them except Bavarian Nordic's JYNNEOS perhaps having a monopoly on this new type for now (they do in the US, don't know about Europe). For the older type vaccine the US started making it again after 9/11 so reclimbing the learning curve was done long ago, there's 100 million doses in our stockpile.