[onphonenow]

From the current data, we can conclude that the tetrahydrocannabinol (THC) component of cannabis can be the main culprit causing psychosis and schizophrenia in the at-risk population. THC can also be the one exacerbating symptoms and causing an adverse prognosis in already diagnosed patients.

It is a well-known fact that many of the abuse substances cause psychosis, which is a part of the schizophrenia spectrum; cannabis is one [9]

Nevertheless, the fact remains that schizophrenia and psychosis walk hand in hand alongside with cannabis use. Cannabis has many strains with different ratios of components. The ratio of THC and CBD is the most important psychotomimetic property of any cannabis strain [14]. When a healthy person uses cannabis, he experiences relaxation, euphoria, and a decrease in anxiety and boredom. However, they might also have some undesirable effects like paranoia, grandiosity, agitation, hallucination, cognitive impairment, disorganized thinking and behavior, and depersonalization [17]. People predisposed to the development of psychotic illness are more vulnerable to the psychotomimetic effects of cannabis, more specifically, THC [16,17].

Per se cannabis does not cause schizophrenia or psychosis. However, we have longitudinal data supporting the causal link between cannabis and psychosis [18].