It's not hub and spoke. Any existing network topology can be mirrored essentially 1:1 with wireguard. With hub and spoke VPNs the model constrains your deployment somewhat. Now I'm not saying key distribution with wireguard is easy, that's a different problem. But wireguard is literally like "let's take your existing network interface and give it modern fast impossible to fuck up encryption".
Traditionally you have a server and all clients connect to this server (Hub and spoke). Wireguard can connect clients like you would in your network. You can mesh clients if you like. The hard part is getting the keys to all peers in the network.