[Eigenstate]

This guy didn't do a lot of research when he picked chronic spontaneous urticaria as the target human indication. There already is an effective biologic, omalizumab, that works on the majority of patients and has no side effects (source: I have CSU/pressure urticaria). Cyclosporine is a heavy duty immunosuppressant with side effects that are worse than hives, imo, so I'm not sure what the target market would be. Personally I'd rather not take the risks of being seriously immunosuppressed, even if it meant getting hives. And, it was the drug my immunologist wanted me to try next if the biologic didn't work, so it's already being prescribed off label.