The purpose is probably to make the home screen symmetrical. Moving the two rightmost columns of app icons two pixels to the right achieves this. Note that previously the outer margins were asymmetrical.
Before iOS5, they were trying to maintain consistent spacing between icons while in iOS5 they changed the home screen margin to be asymmetric while maintaining the same margin ratio between non-Retina and Retina displays. They can't use 35+38+38+38+35 because that would leave non-Retina at 17.5 pixels for left and right margin.
Oh true, missed that. Finally pulled out the phone to realize this. And then the other option 16+20+20+20+16 / 32+40+40+40+32 already has too big a difference between the margins on the edges compared to the ones between the icons. Makes perfect sense now.
Did anyone notice that it was asymmetrical? I know I didn't. And given other mentions of right-handedness in the OS, and the oddity of it being by accident, I'm more than willing to believe it was intentional.
The white plastic Macbook has screws that appear to be purely decorative, on the left side of the case . The story goes that Jobs insisted on them being there, to achieve symmetry with the functional screws on the right hand side.
This [1] was after Jobs stepped down as CEO, but it was obviously being planned while he was chief. The company went to an almost excessive extent in order for the store to be symmetrical.
Also as far as the outer margins are concerned, the badge extends the right side of the icon, so having the right margin wider was reasonable.