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by dekhn 1470 days ago
You're conflating "consequences and effects" with "function". The former is things that happen due to the physics, the latter is about intent or utility.

"Taking up space in the genome is a function" is a great example of this. While I'm sure you can find examples of "spacers that when deleted are fatal", the fitness effect of protein-coding regions that contain no utility is still an area of research. To me, functionality requires selection, although that's probably not necessary or sufficient!