| > stem cell exhaustion if you plug stem cell exhaustion and "telomere" into google, they have relationships in the literature: As a result, the qualitative and quantitative decrease in stem cell function
during the process of aging, known as stem cell exhaustion, has been specified
as one of the promoters of aging (3,6). The role of telomere loss in the
replicative senescence of stem cells has recently been the focus of
considerable interest.
> epigenetic disregulationif you plug epigenetic disregulation and "telomere" into google, they have relationships in the literature. > genomic instability if you plug genomic instability and "telomere" into google, not surprisingly they have relationship. > altered cell signaling I think you can guess what I'm going to say here. I'm not a cell biologist. I certainly don't think telomeres are the smoking gnu of all of this, but there are indications the commonality of how telomeres alter DNA expression, and the centrality of DNA processing to renew cell function come to the fore: if you don't have a valid end-cap on the instruction set, it may not reproduce accurately which affects all the cellular processes which stem from it's reproduction and application. (a massively overplayed analogy to the digital domain, which is a bit bogus) > stem cell |