[copperfoil]

Yes but there’s a price/reliability/performance trade off. Also, with disks that big failures become qualitatively different. For example, when a disk fails in a mirror, the bigger the disk size the higher the chance the 2nd disk will have unreadable blocks.

[kstenerud]

This is what ZFS scrubbing is for. If a drive develops unreadable sectors, ZFS will alert you.

[giantrobot]

If the drives are in a RAID ZFS will not only alert you but fix the corruption from parity on other disks.