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by nokcha 1495 days ago
In regards to the difference in effect between Adderall and illegal street meth, Scott thinks the biggest difference is the dosage size, effectively around 50x higher for street meth: https://astralcodexten.substack.com/p/drug-users-use-a-lot-o...

Dosis sola facit venenum.

2 comments

And particularly the means--smoking it versus taking orally. A lot of these stims are terrible if snorted or injected, they used to warn patients never to do that or risk becoming addicted.

There is a methamphetamine that is prescribed to ADD's, not the same as the street version of course.

This may not actually be the case: https://www.theatlantic.com/magazine/archive/2021/11/the-new...

I've done a decent amount of drugs, and I've been around people who have done a hell of a lot more, but I recently had a friend develop a meth problem, and I have to say, there is something remarkably different about how issue compared to what I've seen in my life.