[passingmagic]

If your primary need is to reduce deployment and maintenance pain, Microsoft 365 (previously called Office 365) with Excel online should work well.

I was drawn to your post since I hate how much Excel is abused. People use a spread sheet where a simple table in a word processor or note taking app more than suffices. Unfortunately I see no way out of it. The replacements to Excel - i.e. other spreadsheet products have the same issue. Excel actually is probably the most mature of the lot with plenty of information to troubleshoot issues.

If you have a good dev team, with good UI design and dev skills, as suggested by @m348e912 you could create a quick app to serve specific purposes. You could also look into other low-code app platforms. These solutions may take a bit to do, but the end users will love it if done right.