[carabiner]

To answer a bunch of questions: Yes, I had bloodwork done later showing my D3 level in the typical range. Whether that was due to the supplement, or diet, or lifestyle I can't say. I take 1 pill (USP certified) on average 2-3x per week. So not every day.

I've got treatment resistant depression and have tried probably everything else you're about to suggest. The only thing that kind of helped was dihydrotestosterone, but that is now illegal in the US. Also tianeptine and vorinostat, but also very hard to get in the US these days.

[trts]

Also in Seattle, also recovered from treatment resistant depression. I recommend looking into TMS. I wish I had done it much sooner.

Wish you luck, it’s been an especially gloomy year here.

[carabiner]

Tried it through Neurostim in Bellevue. Didn't work. Waiting for the Stanford SAINT protocol to be approved.

[tsol]

Did you try vorinostat yourself to treat depression, or was it coincidental? I never heard of that for depression, but looking at the mechanism it can make sense-- some HDAC inhibitors have powerful effects on mental issues

[pmoriarty]

"I've got treatment resistant depression and have tried probably everything else you're about to suggest."

I bet you haven't tried MDMA therapy.

[laurentlbm]

I have TRD too and tried so many things. It sucks.