If anyone were in a position to know whether it’s possible, and how to do it, he’d be on the list.
I think, regardless of his history regarding open source, water under the bridge long ago, he is worth taking seriously if we want to be prepared for the next one, which may come soon.
There was probably a window in time when cases were less than a few thousand or so when such a thing could have been possible. That's the real game in fighting emerging diseases. Early detection, identification of reservoirs and rapid vaccine development and aggressive isolation and ring vaccination if possible.
But I agree, it's absolutely laughable to think enforced social distancing could ever control a fully airborne disease, already so widespread, and with an R_0 over 4, especially now with the current rate of emergence of immunity escaping variants. Check out BA.4 and BA.5 in south africa right now, both of which seem to elude immunity from BA.1 just 6 months after Omicron's emergence.
Sure, it would have originally been rational to try to contain it until widespread vaccination could happen. That was no longer an option as soon as:
(a) Trump decided that his followers should treat it by injecting bleach, fish tank cleaner, and horse dewormer
(b) the WHO and the CDC decided it wasn't an airborne disease because apparently they were still relying on research from 1949 C.E.
(c) the CDC decided not to tell Americans that masks were effective (because they didn't want panic buying)
(d) Biden's COVID czar decided to ostrich the whole thing
Now we're just fucked; everyone will get it, the question is how many times and how bad the next variants. And whether we'll ever develop effective treatment for long covid.
The cat was long already out of the bag at all of those points.
There's a small chance it could have been contained in late 2019 when Wuhan doctors were raising the alarm, but they were silenced and punished by Chinese government officials
That's the thing though. Things like SARS and MERS still exist in the animal reservoirs and could come back at any time. It never hit pandemic or even endemic levels. It's easy to eradicate something in a small geographic area with a small group if people. And you're right, the severity made it much harder for infections to be missed (I think it was less contagious too).
I was just saying that now something has hit pandemic level, it's unlikely we can make it go away. If we're lucky it will end up like the Spanish flu - people build immunity to the current strain during a few years and it mutates to something less severe.
I'm not sure we can, even if we try. At least not for any practical cost. Canada has been trying to curtail, and ideally eradicate, rabies from the wild for the last ~50 years. Rabid animals are systematically culled. There's an oral animal vaccine. There's an ongoing vaccination program where they scatter the vaccine all over the place in edible treat format. The ongoing cost of these programs is considerable, running to hundreds of millions of dollars.
And yet rabies has not been eliminated from the wild. Not by a long shot. The cumulative effect of these programs over the decades is to mostly eradicate it from inhabited areas in foxes, raccoons and other species which are prone to human interaction. Actual eradication of rabies in the wild in North America, is essentially unattainable, even if we scaled current programs up massively. Too many skunks slip through the net. Unless we're going to simply sterilize the outdoors, I'm really not sure we could eradicate animal reservoirs for COVID-19.
No we couldn't have. It's never been done in history and is probably impossible to do.